INT224675

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.94
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (S100a4, Mmp3) peptidase activity (Mmp3) extracellular space (Mmp3)
extracellular region (Mmp3) proteinaceous extracellular matrix (Mmp3) protein complex (Mmp3)
Anatomy Link Frequency
extracellular matrix 1
S100a4 (Mus musculus)
Mmp3 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 52 96.12 Very High Very High Very High
metalloproteinase 25 90.24 High High
cINOD 1 25.64 Quite Low
Inflammation 24 21.16 Low Low
COX-2 inhibitor 2 11.56 Low Low
cytokine 29 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 7 100.00 Very High Very High Very High
Metastasis 2 99.60 Very High Very High Very High
Disease 11 98.36 Very High Very High Very High
Malignant Neoplastic Disease 1 98.00 Very High Very High Very High
Rheumatoid Arthritis 52 96.12 Very High Very High Very High
Severe Combined Immunodeficiency 8 59.20 Quite High
INFLAMMATION 25 25.40 Quite Low
Apoptosis 28 12.28 Low Low
Adhesions 7 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The metastasis-associated protein S100A4, which promotes the progression of cancer by regulating remodelling of the extracellular matrix, upregulated MMP-3 mRNA and protein in RASFs.
S100A4 Positive_regulation (upregulated) of MMP-3 in extracellular matrix associated with cancer and metastasis
1) Confidence 0.04 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.94 Pain Relevance 0.48

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox