INT224699

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il18, VEGFA) extracellular region (Il18, VEGFA) cytoplasm (Il18, VEGFA)
growth (VEGFA) proteinaceous extracellular matrix (VEGFA)
Il18 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 52 93.28 High High
cytokine 29 93.04 High High
chemokine 5 78.76 Quite High
Inflammation 24 53.00 Quite High
metalloproteinase 25 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 52 93.28 High High
Apoptosis 28 67.28 Quite High
INFLAMMATION 25 53.00 Quite High
Disease 11 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 8 5.00 Very Low Very Low Very Low
Adhesions 7 5.00 Very Low Very Low Very Low
Cancer 7 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both IL-17 and IL-18 increased the synthesis of the proangiogenic factor VEGF, and IL-20 promoted enhanced chemotaxis via MCP-1 and IL-8 [33-35].
IL-18 Positive_regulation (increased) of Gene_expression (synthesis) of VEGF
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.49 Pain Relevance 0.46

General Comments

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