INT224724

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.57
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Metap2) molecular_function (Gm2458) cellular_component (Gm2458)
cytoplasm (Metap2) biological_process (Gm2458)
Gm2458 (Mus musculus)
Metap2 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 84 98.96 Very High Very High Very High
rheumatoid arthritis 46 96.88 Very High Very High Very High
Inflammation 15 34.56 Quite Low
chemokine 8 18.72 Low Low
cytokine 13 11.92 Low Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 87 98.96 Very High Very High Very High
Rheumatoid Arthritis 47 96.88 Very High Very High Very High
Disease 24 95.64 Very High Very High Very High
Immunization 5 93.04 High High
Disease Progression 2 80.24 Quite High
Diabetes Mellitus 1 58.44 Quite High
Pressure And Volume Under Development 6 50.80 Quite High
INFLAMMATION 17 34.56 Quite Low
Cancer 6 5.00 Very Low Very Low Very Low
Erythema 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We report that PPI-2458, an inhibitor of MetAP-2, not only inhibits acute CIA model but also has profound effect on the pathology of chronic CIA.
PPI-2458 Negative_regulation (inhibitor) of MetAP-2 associated with arthritis
1) Confidence 0.02 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246249 Disease Relevance 1.57 Pain Relevance 0.57

General Comments

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