INT2249

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.54
First Reported 1979
Last Reported 2010
Negated 1
Speculated 2
Reported most in Body
Documents 5
Total Number 8
Disease Relevance 6.82
Pain Relevance 2.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-B)
Anatomy Link Frequency
bowel 2
HLA-B (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 240 100.00 Very High Very High Very High
spinal inflammation 75 100.00 Very High Very High Very High
Inflammation 23 100.00 Very High Very High Very High
spondylitis 3 100.00 Very High Very High Very High
methotrexate 84 99.40 Very High Very High Very High
Etanercept 12 99.04 Very High Very High Very High
psoriasis 1 97.98 Very High Very High Very High
cINOD 2 91.76 High High
rheumatoid arthritis 17 5.92 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Juvenile Chronic Polyarthritis 180 100.00 Very High Very High Very High
Seronegative Spondarthritis 142 100.00 Very High Very High Very High
Arthritis 82 100.00 Very High Very High Very High
Low Back Pain 55 100.00 Very High Very High Very High
INFLAMMATION 23 100.00 Very High Very High Very High
Rheumatic Diseases 8 100.00 Very High Very High Very High
Congenital Anomalies 1 100.00 Very High Very High Very High
Inflammatory Bowel Disease 2 98.60 Very High Very High Very High
Psoriasis 1 97.98 Very High Very High Very High
Ankylosing Spondylitis 3 97.38 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Secondary forms of peripheral arthritis, radiographic sacroiliitis, and ankylosing spondylitis frequently occur in psoriasis and inflammatory bowel disease; in the case of peripheral arthritis, there is no or a significantly reduced association with HLA-B27 compared to AS or RS.
Negative_regulation (reduced) of HLA-B27 Neg (no) Binding (association) of in bowel associated with psoriasis, spinal inflammation, sacroiliitis, inflammation and arthritis
1) Confidence 0.54 Published 1979 Journal Clin. Orthop. Relat. Res. Section Abstract Doc Link 389516 Disease Relevance 1.42 Pain Relevance 0.44
Possible interactions of HLA-B7 and HLA-Cw*0702 with other factors
Spec (Possible) Negative_regulation (Possible) of HLA-B7 Binding (interactions) of
2) Confidence 0.42 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1764414 Disease Relevance 0.23 Pain Relevance 0
Division of HLA B27 positive JIA patient by sex
Negative_regulation (Division) of HLA B27 Binding (patient) of associated with seronegative spondarthritis and arthritis
3) Confidence 0.39 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2964715 Disease Relevance 1.78 Pain Relevance 0.68
Division of HLA B27 positive JIA patient in groups
Negative_regulation (Division) of HLA B27 Binding (patient) of associated with seronegative spondarthritis and arthritis
4) Confidence 0.39 Published 2010 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2964715 Disease Relevance 1.48 Pain Relevance 0.61
[Ankylosing spondylitis and heterogenity of HLA-B27 in Chinese].
Negative_regulation ([Ankylosing) of HLA-B27 Binding (heterogenity) of associated with spinal inflammation
5) Confidence 0.35 Published 1996 Journal Zhonghua Wai Ke Za Zhi Section Title Doc Link 9594171 Disease Relevance 0.43 Pain Relevance 0.48
Anchor residues at position P7 and P8 of some viral peptides may prevent KIR3DL1-mediated recognition of HLA-B27.
Spec (may) Negative_regulation (prevent) of HLA-B27 Binding (recognition) of
6) Confidence 0.33 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1779409 Disease Relevance 0.40 Pain Relevance 0.11
They are characterized by an association with the cell surface antigen HLA-B27, sacroilitis and spondylitis, inflammatory peripheral arthritis, enthesopathy (abnormalities in ligamentous attachments), and the absence of rheumatoid factor.
Negative_regulation (absence) of HLA-B27 Binding (association) of associated with spondylitis, inflammation, congenital anomalies, rheumatic diseases and arthritis
7) Confidence 0.12 Published 1984 Journal Prim. Care Section Abstract Doc Link 6332327 Disease Relevance 0.97 Pain Relevance 0.43
[Study on the association of transporter associated with antigen processing gene with ankylosing spondylitis and HLA-B27 in Han nationality].
Negative_regulation (ankylosing) of HLA-B27 Binding (spondylitis) of associated with spinal inflammation
8) Confidence 0.01 Published 2001 Journal Zhonghua Yi Xue Yi Chuan Xue Za Zhi Section Title Doc Link 11402452 Disease Relevance 0.10 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox