INT224949

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Tpr) molecular_function (Tpr)
Anatomy Link Frequency
myeloid cell 2
ovary 2
Tpr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 80.52 Quite High
Neurobehavioral 6 18.56 Low Low
metalloproteinase 32 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
tolerance 10 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 8 99.44 Very High Very High Very High
Targeted Disruption 8 99.30 Very High Very High Very High
Obesity 150 95.08 Very High Very High Very High
Insulin Resistance 34 94.12 High High
INFLAMMATION 38 80.52 Quite High
Stress 8 70.16 Quite High
Weight Gain 2 63.84 Quite High
Disorder Of Lipid Metabolism 1 62.56 Quite High
Atherosclerosis 4 60.12 Quite High
Hyperphagia 24 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As previously shown, crossing IRflox/flox-mice with mice expressing the Cre-recombinase under control of the lysozymeM promoter resulted in efficient, myeloid cell-restricted ablation of the insulin receptor [19] (Figure 1A and 1B).
Regulation (under) of Regulation (control) of lysozymeM promoter in myeloid cell
1) Confidence 0.01 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2865520 Disease Relevance 1.30 Pain Relevance 0.07
Heterozygous 2-loxP mice were mated to a transgenic strain expressing Cre recombinase under the control of the ovary-specific Zp3 promoter on a C57BL/6J background.
Regulation (under) of Regulation (control) of Zp3 promoter in ovary associated with targeted disruption and sprains and strains
2) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248623 Disease Relevance 0.27 Pain Relevance 0

General Comments

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