INT2250

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Context Info
Confidence 0.47
First Reported 1979
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 3.58
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (REG3A) extracellular space (REG3A) extracellular region (REG3A)
cytoplasm (REG3A)
Anatomy Link Frequency
hip 5
Shelf 1
REG3A (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 294 100.00 Very High Very High Very High
cINOD 4 98.64 Very High Very High Very High
Pain 7 93.04 High High
Inflammation 4 81.84 Quite High
visual analogue scale 3 26.40 Quite Low
Disease Link Frequency Relevance Heat
Canine Hip Dysplasia 188 100.00 Very High Very High Very High
Hip Osteoarthritis 10 100.00 Very High Very High Very High
Osteoarthritis 284 99.96 Very High Very High Very High
Cleidocranial Dysplasia 21 99.96 Very High Very High Very High
INFLAMMATION 5 97.92 Very High Very High Very High
Disease 29 96.68 Very High Very High Very High
Pain 7 93.04 High High
Injury 12 88.56 High High
Apoptosis 4 80.28 Quite High
Stress 4 79.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These correspond to regions where our microsatellite screen showed association with hip OA.
hip Binding (association) of in hip associated with osteoarthritis
1) Confidence 0.47 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2952589 Disease Relevance 0.30 Pain Relevance 0.10
Shelf reconstruction for hip dysplasia.
hip Binding (reconstruction) of in Shelf associated with cleidocranial dysplasia
2) Confidence 0.36 Published 1979 Journal South. Med. J. Section Title Doc Link 390715 Disease Relevance 0.19 Pain Relevance 0.09
Hip OA is generally managed with systemic treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs) and/or symptomatic slow acting drugs.
Hip Binding (managed) of in Hip associated with inflammation, cinod and osteoarthritis
3) Confidence 0.36 Published 2005 Journal Clin. Rheumatol. Section Abstract Doc Link 15592903 Disease Relevance 0.70 Pain Relevance 0.45
In our study, its homologous gene in dog was associated with hip OA.
hip Binding (associated) of in hip associated with osteoarthritis
4) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2952589 Disease Relevance 1.72 Pain Relevance 0.47
We expect that the current population would have more statistical power to reveal more SNPs associated with HD and hip OA if more dense markers were applied through new genotyping technology such as application of the version 2 canine Illumina Beadarray or genotyping by sequencing [53] and if more dogs were included in the GWAS.
hip Binding (associated) of in hip associated with canine hip dysplasia and osteoarthritis
5) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2952589 Disease Relevance 0.26 Pain Relevance 0.08
The power to detect association for hip OA in our report was a limiting factor as only 99 dogs were available for this analysis and only the Labrador retrievers and the crosses to Greyhounds were included for this phenotype.
hip Binding (association) of in hip associated with osteoarthritis
6) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2952589 Disease Relevance 0.41 Pain Relevance 0.14

General Comments

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