INT225013

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Context Info
Confidence 0.33
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.15
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl5) extracellular region (Cxcl5)
Anatomy Link Frequency
smooth muscle cells 1
Cxcl5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 135 100.00 Very High Very High Very High
Glutamate 10 100.00 Very High Very High Very High
Inflammation 15 31.00 Quite Low
cytokine 10 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
isoflurane 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 15 75.32 Quite High
INFLAMMATION 15 31.00 Quite Low
Wound Healing 10 9.08 Low Low
Myocardial Infarction 10 5.00 Very Low Very Low Very Low
Diabetic Foot Ulcer 5 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, CXCL5 gene expression in the groups containing 25 µg PDGF encapsulated in PLGA microspheres was higher than that of the scaffold alone group and the two PDGF coating groups, while the group containing 25 µg PDGF encapsulated in HMW PLGA microspheres also had more CXCL5 gene expression, compared to 2.5 µg PDGF encapsulated in the LMW PLGA microspheres group.
Gene_expression (expression) of CXCL5
1) Confidence 0.33 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0 Pain Relevance 0.07
In addition, CXCL5 gene expression in the groups containing 25 µg PDGF encapsulated in PLGA microspheres was higher than that of the scaffold alone group and the two PDGF coating groups, while the group containing 25 µg PDGF encapsulated in HMW PLGA microspheres also had more CXCL5 gene expression, compared to 2.5 µg PDGF encapsulated in the LMW PLGA microspheres group.
Gene_expression (expression) of CXCL5
2) Confidence 0.33 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0 Pain Relevance 0.10
Results from cDNA array showed that PDGF strongly enhanced in vivo gene expression of the CXC chemokine family members such as CXCL1, CXCL2 and CXCL5.
Gene_expression (expression) of CXCL5 associated with chemokine
3) Confidence 0.30 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2248711 Disease Relevance 0.08 Pain Relevance 0.13
In addition, CXCR2 is demonstrated to be the receptor responsible for ELR(+) CXC chemokine-mediated angiogenesis.[38] ELR motif: (glutamate-leucine-arginine motif) PDGF and CXC chemokines may have synergistic effects on angiogenesis, because the PDGF effects focus on pericytes and vascular smooth muscle cells and improve blood vessel growth, while ELR(+) CXC chemokine primarily affects endothelial cells. [38], [39]
Gene_expression (focus) of CXC chemokine in smooth muscle cells associated with chemokine and glutamate
4) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2248711 Disease Relevance 0 Pain Relevance 0.42
Results from cDNA array showed that PDGF strongly enhanced in vivo gene expression of the CXC chemokine family members such as CXCL1, CXCL2 and CXCL5.
Gene_expression (expression) of CXC chemokine associated with chemokine
5) Confidence 0.26 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2248711 Disease Relevance 0.08 Pain Relevance 0.13

General Comments

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