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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.34
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CAMK4) nucleoplasm (CAMK4) signal transduction (CAMK4)
nucleus (CAMK4) cytoplasm (CAMK4)
Anatomy Link Frequency
liver 1
CAMK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 97.00 Very High Very High Very High
antagonist 3 90.52 High High
member 8 1 89.80 High High
addiction 7 87.84 High High
GABAergic 5 73.08 Quite High
tolerance 4 18.00 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
iatrogenic 2 5.00 Very Low Very Low Very Low
Somatostatin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 2 99.98 Very High Very High Very High
Adhesions 1 97.54 Very High Very High Very High
Diabetes Mellitus 96 96.22 Very High Very High Very High
Increased Venous Pressure Under Development 3 67.60 Quite High
Blindness 1 66.52 Quite High
Renal Failure 1 66.08 Quite High
Disease 12 58.84 Quite High
Injury 10 50.00 Quite Low
Renal Disease 1 21.92 Low Low
Hyperplasia 1 19.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, inhibitors of nitric oxide synthase (NOS), phosphotidylinositol-3-kinase (PI3K), and CAMK exhibited less prevalent, gene-specific effects on BDNF-induced RNA expression.
Negative_regulation (inhibitors) of CAMK
1) Confidence 0.04 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2669182 Disease Relevance 0.06 Pain Relevance 0.22
Among the most highly dysregulated diabetes-associated genes were protein kinase C and vascular cell adhesion molecule in aorta, retinol-binding protein and angiopoietin-like protein in kidney, lipoprotein lipase and apolipoprotein A-IV in liver, vasoactive intestinal peptide receptor and serpin peptidase inhibitor in retina.
Negative_regulation (inhibitor) of A-IV in liver associated with kinase c, diabetes mellitus, disorder of lipid metabolism and adhesions
2) Confidence 0.01 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249706 Disease Relevance 1.28 Pain Relevance 0.05

General Comments

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