INT225067

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 4.52
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ETF1) extracellular region (IGHG3) RNA binding (ETF1)
translation (ETF1) cytoplasm (ETF1)
ETF1 (Homo sapiens)
IGHG3 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 6 100.00 Very High Very High Very High
Chronic pancreatitis 30 84.56 Quite High
alcohol 6 78.88 Quite High
Arthritis 6 71.44 Quite High
imagery 18 71.28 Quite High
Inflammation 24 39.28 Quite Low
fibrosis 12 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Prostatitis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 12 100.00 Very High Very High Very High
Autoimmune Disease 42 96.60 Very High Very High Very High
Pancreatitis 198 92.96 High High
Alcohol Addiction 6 78.88 Quite High
Targeted Disruption 6 61.48 Quite High
Pressure And Volume Under Development 12 53.28 Quite High
Disease 66 49.84 Quite Low
Hypergammaglobulinemia 6 44.64 Quite Low
INFLAMMATION 30 39.28 Quite Low
Obstructive Jaundice 6 20.24 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It should be also reminded that a previous report, albeit in vitro, did show through domain swapping experiments that the binding of a monoclonal IgG4 RF (isolated this time from a rheumatoid arthritis patient) to IgG is through their respective constant segments and not Fab-Fc [40].
RF Binding (binding) of IgG associated with rheumatoid arthritis
1) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249926 Disease Relevance 0.17 Pain Relevance 0.09
The interaction between the RF and IgG is well documented; the RF Fab (antigen binding site) recognizes IgG Fc (constant) segment most frequently at the level of C?
RF Binding (interaction) of IgG
2) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249926 Disease Relevance 0.81 Pain Relevance 0.20
The interaction between the RF and IgG is well documented; the RF Fab (antigen binding site) recognizes IgG Fc (constant) segment most frequently at the level of C?
RF Binding (recognizes) of IgG
3) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249926 Disease Relevance 0.89 Pain Relevance 0.22
The interaction between the RF and IgG is well documented; the RF Fab (antigen binding site) recognizes IgG Fc (constant) segment most frequently at the level of C?
RF Binding (recognizes) of IgG
4) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249926 Disease Relevance 0.89 Pain Relevance 0.22
The interaction between the RF and IgG is well documented; the RF Fab (antigen binding site) recognizes IgG Fc (constant) segment most frequently at the level of C?
RF Binding (recognizes) of IgG
5) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249926 Disease Relevance 0.88 Pain Relevance 0.22
The interaction between the RF and IgG is well documented; the RF Fab (antigen binding site) recognizes IgG Fc (constant) segment most frequently at the level of C?
RF Binding (recognizes) of IgG
6) Confidence 0.02 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2249926 Disease Relevance 0.88 Pain Relevance 0.22

General Comments

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