INT225124

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.77
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tg) extracellular region (Tg) Golgi apparatus (Tg)
endoplasmic reticulum (Tg)
Anatomy Link Frequency
neurons 1
pituitary 1
Tg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 2 86.56 High High
Kinase C 30 74.96 Quite High
Neuropeptide 4 62.48 Quite High
Dopamine 62 50.00 Quite Low
fibrosis 1 27.52 Quite Low
gABA 4 5.00 Very Low Very Low Very Low
Neurotransmitter 4 5.00 Very Low Very Low Very Low
addiction 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cocaine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thyroid Neoplasm 19 95.36 Very High Very High Very High
Skin Cancer 7 93.76 High High
Cancer 24 86.16 High High
Rhinitis 3 81.80 Quite High
Alzheimer's Dementia 3 57.08 Quite High
Carcinoma 4 48.00 Quite Low
Metastasis 6 32.60 Quite Low
Cystic Fibrosis 1 28.08 Quite Low
Obstructive Airway Disease 1 26.72 Quite Low
Recurrence 3 26.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, the TGN is known to interact with the recycling endosomal system in hippocampal neurons [50].
TGN Binding (interact) of in neurons
1) Confidence 0.06 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.11
Interestingly, the membrane form of CPE has been demonstrated to bind to POMC [30] and BDNF [41], sorting these precursors at the trans-Golgi network (TGN) into vesicles of the regulated secretory pathway in pituitary cells and hippocampal neurons, respectively.
TGN Binding (bind) of in pituitary
2) Confidence 0.04 Published 2009 Journal Mol Brain Section Body Doc Link PMC2687442 Disease Relevance 0 Pain Relevance 0.10
MTCs are generally negative for thyroglobulin as has been seen in the present case [17].
thyroglobulin Binding (negative) of
3) Confidence 0.02 Published 2008 Journal Diagn Pathol Section Body Doc Link PMC2253502 Disease Relevance 0.77 Pain Relevance 0

General Comments

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