INT225160

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CDK2, CDKN1A) cytoplasm (CDK2, CDKN1A) cytosol (CDK2, CDKN1A)
nucleus (CDK2, CDKN1A) cell cycle (CDK2, CDKN1A) kinase activity (CDK2, CDKN1A)
CDK2 (Homo sapiens)
CDKN1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 13 70.08 Quite High
antagonist 4 63.44 Quite High
narcan 9 62.56 Quite High
opioid receptor 8 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
Endogenous opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 12 40.00 Quite Low
Retinoblastoma 26 29.48 Quite Low
Pancreatic Cancer 35 5.00 Very Low Very Low Very Low
Adenocarcinoma 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Skin Cancer 1 5.00 Very Low Very Low Very Low
Colon Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because p21 inhibits Cdk2 by physical interaction, we examined whether the OGF-induced downregulation of Cdk2 kinase activity was based on p21/Cdk2 complex formation.
Negative_regulation (downregulation) of Cdk2 Binding (formation) of p21
1) Confidence 0.35 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2253554 Disease Relevance 0 Pain Relevance 0.25

General Comments

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