INT225218

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Nf2) nucleolus (Nf2) plasma membrane (Nf2)
cytoskeleton (Nf2) nucleus (Nf2) protein complex (Nf2)
Anatomy Link Frequency
plaque 2
Nf2 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 4 88.64 High High
Inflammation 1 47.48 Quite Low
cva 1 46.60 Quite Low
imagery 31 19.76 Low Low
trigeminal ganglion 2 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Meningioma 91 98.78 Very High Very High Very High
Hyperostosis 2 94.52 High High
Cancer 38 92.00 High High
Hyperplasia 4 67.20 Quite High
Chronic Renal Failure 1 51.32 Quite High
INFLAMMATION 1 47.48 Quite Low
Hemorrhage 1 46.60 Quite Low
Injury 1 46.12 Quite Low
Nerve Sheath Neoplasms 1 27.04 Quite Low
Neurofibromatosis 2 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The higher frequency of en plaque meningiomas in our mouse model is likely caused by the multifocality of Nf2 inactivation induced by diffusion in the subarachnoid space of the highly concentrated adCre vector suspension.
Positive_regulation (induced) of Negative_regulation (inactivation) of Nf2 in plaque associated with meningioma
1) Confidence 0.40 Published 2008 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC2253711 Disease Relevance 1.07 Pain Relevance 0.04

General Comments

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