INT225220

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ccnd1) intracellular (Ccnd1) enzyme binding (Ccnd1)
cell cycle (Ccnd1) cell division (Ccnd1) kinase activity (Ccnd1)
Ccnd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 4 40.72 Quite Low
imagery 31 28.36 Quite Low
fifth nerve 2 20.88 Low Low
trigeminal ganglion 2 14.56 Low Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Meningioma 91 98.88 Very High Very High Very High
Neurofibromatosis 2 9 87.92 High High
Cancer 38 83.56 Quite High
Malignant Neoplastic Disease 2 82.56 Quite High
Spinal Cord Compression 1 32.92 Quite Low
Paraparesis 1 30.52 Quite Low
Ganglion Cysts 2 14.56 Low Low
Metaplasia 3 13.48 Low Low
Targeted Disruption 3 9.28 Low Low
Hyperplasia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the synergy we observed between Nf2 and p16Ink4 mutations in meningioma development reflects the concomitant loss of two regulators of CDK4 activity resulting in cyclin D1 activation.
Positive_regulation (resulting) of Positive_regulation (activation) of cyclin D1 associated with meningioma
1) Confidence 0.14 Published 2008 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC2253711 Disease Relevance 1.20 Pain Relevance 0

General Comments

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