INT225223

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cdkn2b) cell cycle (Cdkn2b) kinase activity (Cdkn2b)
cytoplasm (Cdkn2b)
Cdkn2b (Mus musculus)
Pain Link Frequency Relevance Heat
fluoxetine 10 93.52 High High
Serotonin 33 58.64 Quite High
Central nervous system 2 40.24 Quite Low
imagery 31 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Raphe 4 5.00 Very Low Very Low Very Low
trigeminal ganglion 2 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Meningioma 91 99.52 Very High Very High Very High
Monosomy 1 91.84 High High
Chromosome Aberrations 1 87.64 High High
Recurrence 1 83.12 Quite High
Targeted Disruption 3 65.52 Quite High
Retinoblastoma 1 63.28 Quite High
Cancer 38 61.84 Quite High
Neurofibromatosis 2 9 61.56 Quite High
Apoptosis 1 47.52 Quite Low
Central Nervous System Cancer 2 40.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The majority of grade III meningiomas either show homozygous deletions of p16INK4a,p14ARF, and CDKN2B, mutations in p16INK4a and p14ARF, or lack of expression of one or more of these genes (3).
Localization (deletions) of CDKN2B associated with meningioma
1) Confidence 0.62 Published 2008 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC2253711 Disease Relevance 1.29 Pain Relevance 0
In the contralateral SC of P15 mice electroporated with Zic2/EGFP, we focused our analysis in the caudal collicular areas (Figure 7D and E) that contain the axons with a defect in refinement.
Localization (electroporated) of P15
2) Confidence 0.16 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0 Pain Relevance 0.37

General Comments

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