INT225226

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.18
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ccnd1) intracellular (Ccnd1) enzyme binding (Ccnd1)
cell cycle (Ccnd1) cell division (Ccnd1) kinase activity (Ccnd1)
Ccnd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 4 52.32 Quite High
imagery 31 39.96 Quite Low
fifth nerve 2 32.48 Quite Low
trigeminal ganglion 2 26.16 Quite Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurofibromatosis 2 9 99.76 Very High Very High Very High
Cancer 38 95.16 Very High Very High Very High
Meningioma 91 86.32 High High
Malignant Neoplastic Disease 2 72.92 Quite High
Spinal Cord Compression 1 44.52 Quite Low
Paraparesis 1 42.12 Quite Low
Ganglion Cysts 2 26.16 Quite Low
Metaplasia 3 25.08 Quite Low
Targeted Disruption 3 20.88 Low Low
Hyperplasia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown previously that NF2 expression induces a decrease in cyclin D1 and CDK4 kinase activity, concomitant with dephosphorylation of pRB and reduced DNA synthesis (9, 28).
Positive_regulation (induces) of Negative_regulation (decrease) of cyclin D1 associated with neurofibromatosis 2
1) Confidence 0.14 Published 2008 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC2253711 Disease Relevance 1.18 Pain Relevance 0.03

General Comments

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