INT225227

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Context Info
Confidence 0.65
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 4.49
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (NF2) nucleolus (NF2) plasma membrane (NF2)
cytoskeleton (NF2) nucleus (NF2) cytoplasm (NF2)
Anatomy Link Frequency
interdigitating cell 1
NF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 2 62.32 Quite High
imagery 36 14.40 Low Low
Spinal cord 4 7.08 Low Low
Inflammation 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
positron emission tomography 2 5.00 Very Low Very Low Very Low
trigeminal ganglion 2 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Vascular Dementia 5 99.96 Very High Very High Very High
Disease 69 99.60 Very High Very High Very High
Malignant Neoplastic Disease 44 99.44 Very High Very High Very High
Meningioma 91 99.12 Very High Very High Very High
Mesothelioma 220 99.04 Very High Very High Very High
Neurofibromatosis 2 15 94.88 High High
Cancer 104 93.68 High High
Dementia 7 91.48 High High
Adhesions 2 85.52 High High
Alzheimer's Dementia 1 75.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Diagnostic ultrastructural features of meningioma, including interdigitating cell processes and desmosomal intercellular junctions, were found in one adCre;Nf2flox2/flox22;Ink4a*/* mouse meningioma analyzed by electron microscopy (Figure 1D,E).
Gene_expression (/) of Nf2 in interdigitating cell associated with meningioma
1) Confidence 0.65 Published 2008 Journal Brain Pathology (Zurich, Switzerland) Section Body Doc Link PMC2253711 Disease Relevance 1.24 Pain Relevance 0
In accordance with some (Arai et al 1998) but not all previous studies (Skoog et al 1995; Andreasen et al 1998; Tapiola et al 1998) we found previously significantly elevated tau levels in AD compared with VaD (Schรถnknecht et al 2003b).
Gene_expression (nknecht) of Sch associated with vascular dementia and disease
2) Confidence 0.65 Published 2006 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2671784 Disease Relevance 1.30 Pain Relevance 0.03
Through the use of in vitro assays, Poulikakos et al. [38] found that the re-expression of merlin in two human malignant mesothelioma cell lines significantly decreased cell motility and invasion.
Gene_expression (expression) of merlin associated with malignant neoplastic disease and mesothelioma
3) Confidence 0.58 Published 2008 Journal J Carcinog Section Body Doc Link PMC2507706 Disease Relevance 0.98 Pain Relevance 0
Through the use of in vitro assays, Poulikakos et al. [38] found that the re-expression of merlin in two human malignant mesothelioma cell lines significantly decreased cell motility and invasion.
Gene_expression (-) of merlin associated with malignant neoplastic disease and mesothelioma
4) Confidence 0.58 Published 2008 Journal J Carcinog Section Body Doc Link PMC2507706 Disease Relevance 0.98 Pain Relevance 0

General Comments

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