INT225407

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.16
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ncoa6) enzyme binding (Ncoa6) protein complex (Ncoa6)
Ncoa6 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 10 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 5 81.84 Quite High
Targeted Disruption 120 38.32 Quite Low
Apoptosis 90 26.00 Quite Low
Retinoblastoma 5 17.16 Low Low
Wound Healing 75 5.00 Very Low Very Low Very Low
Breast Cancer 40 5.00 Very Low Very Low Very Low
Cancer 35 5.00 Very Low Very Low Very Low
Obesity 25 5.00 Very Low Very Low Very Low
Repression 20 5.00 Very Low Very Low Very Low
Shock 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Embedded in this region is the LxxLL-1 motif, which is involved in NR interaction, but not homodimerization of NCoA6(NRC), as suggested by mutational analysis and dimerization data.
Regulation (involved) of NRC Neg (not) Binding (homodimerization) of
1) Confidence 0.44 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0 Pain Relevance 0
Embedded in this region is the LxxLL-1 motif, which is involved in NR interaction, but not homodimerization of NCoA6(NRC), as suggested by mutational analysis and dimerization data.
Regulation (involved) of NCoA6 Neg (not) Binding (homodimerization) of
2) Confidence 0.44 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0 Pain Relevance 0
Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development


Regulation (coregulator) of NRC Binding (receptor) of
3) Confidence 0.44 Published 2008 Journal Nuclear Receptor Signaling Section Title Doc Link PMC2254332 Disease Relevance 0.08 Pain Relevance 0
The composition of these complexes is similar but not identical, invoking the possibility that association of NCoA6 with these complexes may be regulated in a cell type- or target gene-specific manner.
Regulation (regulated) of NCoA6 Binding (association) of
4) Confidence 0.44 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0 Pain Relevance 0
Nuclear receptor coactivator/coregulator NCoA6(NRC) is a pleiotropic coregulator involved in transcription, cell survival, growth and development


Regulation (coregulator) of NCoA6 Binding (receptor) of
5) Confidence 0.38 Published 2008 Journal Nuclear Receptor Signaling Section Title Doc Link PMC2254332 Disease Relevance 0.08 Pain Relevance 0

General Comments

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