INT225413

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.27
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Srf) nucleus (Srf) DNA binding (Srf)
transcription factor binding (Srf) cytoplasm (Srf)
Srf (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 66.96 Quite High
Paracetamol 2 49.48 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 3 100.00 Very High Very High Very High
Apoptosis 18 62.48 Quite High
Targeted Disruption 24 56.92 Quite High
Necrosis 1 50.48 Quite High
Hepatotoxicity 1 22.28 Low Low
Wound Healing 15 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Cancer 7 5.00 Very Low Very Low Very Low
Obesity 5 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although NCoA6 was initially cloned as coactivator protein for NRs, its detailed characterization by a number of laboratories has uncovered its potential to enhance the activity of a wide variety of other transcription factors including c-Fos, c-Jun, CREB, NF-kB, ATF-2, heat shock factors, E2F-1, SRF, and Rb, p53 and Sox9 [Goo et al., 2004; Hong et al., 2004a; Hong et al., 2004b; Ko et al., 2000; Kong et al., 2003; Lee et al., 1999; Lee et al., 2000; Mahajan et al., 2007; Mahajan et al., 2002; Mahajan and Samuels, 2000; Mahajan and Samuels, 2005].
SRF Binding (enhance) of associated with shock
1) Confidence 0.10 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0.27 Pain Relevance 0.03

General Comments

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