INT225450

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ncoa1) nucleus (Ncoa1) transferase activity, transferring acyl groups (Ncoa1)
DNA binding (Ncoa1) signal transducer activity (Ncoa1)
Ncoa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 4 100.00 Very High Very High Very High
Targeted Disruption 24 94.96 High High
Cataract 1 89.44 High High
Microphthalmia 1 87.88 High High
Congenital Anomalies 1 82.08 Quite High
Apoptosis 18 36.32 Quite Low
Wound Healing 15 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Cancer 7 5.00 Very Low Very Low Very Low
Obesity 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both DN1 and DN2 caused repression of some NR-mediated target gene expression, which was found to be completely reversed by co-transfection of wild-type NCoA6(ASC-2), but not by co-expression of other coactivators such as TRAP220 or SRC-1.
Negative_regulation (repression) of Gene_expression (expression) of SRC-1 associated with repression
1) Confidence 0.06 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0.97 Pain Relevance 0

General Comments

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