INT225509

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Context Info
Confidence 0.11
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ncoa6) enzyme binding (Ncoa6) protein complex (Ncoa6)
nr (Mus musculus)
Ncoa6 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 48 91.76 High High
Apoptosis 36 80.88 Quite High
Repression 8 71.20 Quite High
Cataract 2 60.24 Quite High
Microphthalmia 2 58.68 Quite High
Congenital Anomalies 2 52.88 Quite High
Wound Healing 30 5.00 Very Low Very Low Very Low
Breast Cancer 16 5.00 Very Low Very Low Very Low
Cancer 14 5.00 Very Low Very Low Very Low
Obesity 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the phenotypes may result not just from inhibition of NCoA6(ASC-2)-NR interaction, but also from inactivation of a number of receptors that bind DN1 in vivo.
Negative_regulation (inhibition) of NR Binding (interaction) of NCoA6
1) Confidence 0.11 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0.79 Pain Relevance 0
(L398R), or deletion of helix 12, abolish the association of the NR with NCoA6(NRC) in vitro and in vivo [Mahajan and Samuels, 2000].
Negative_regulation (abolish) of NR Binding (association) of NCoA6
2) Confidence 0.08 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0 Pain Relevance 0

General Comments

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