INT225616

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

D0Nrs1 (Mus musculus)
IGHD6-13 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 24 93.60 High High
Cancer 7 15.12 Low Low
Apoptosis 18 5.00 Very Low Very Low Very Low
Wound Healing 15 5.00 Very Low Very Low Very Low
Breast Cancer 8 5.00 Very Low Very Low Very Low
Obesity 5 5.00 Very Low Very Low Very Low
Repression 4 5.00 Very Low Very Low Very Low
Shock 3 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Insulin Resistance 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since DN1 containing LxxLL-1 and DN2 containing LxxLL-2 would be expected to compete with the binding of other coactivators for liganded NRs, the mechanism(s) by which these LxxLL regions specifically block the activity of NCoA6(ASC-2), but not other coactivators, is unclear and requires further study.
NRs Binding (binding) of DN1
1) Confidence 0.02 Published 2008 Journal Nuclear Receptor Signaling Section Body Doc Link PMC2254332 Disease Relevance 0.42 Pain Relevance 0

General Comments

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