INT225648

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL4, IL12A) extracellular region (IL4, IL12A) cytoplasm (IL12A)
Anatomy Link Frequency
fibroblasts 2
IL4 (Homo sapiens)
IL12A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 10 59.80 Quite High
imagery 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Glioma 39 99.08 Very High Very High Very High
Cancer 54 88.72 High High
Cold Sores 1 73.92 Quite High
Herpes Simplex Virus 1 73.04 Quite High
Glioblastoma 7 38.72 Quite Low
Anaplastic Astrocytoma 4 38.16 Quite Low
Immunization 9 32.44 Quite Low
Gliosarcoma 1 29.08 Quite Low
Melanoma 2 19.64 Low Low
Infection 1 15.28 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As IL-4 promotes maturation and IL-12 production of DCs, we subsequently developed another trial for patients with newly diagnosed malignant glioma, using TFG-hIL4-Neo-TK-transfected fibroblasts and type-1-promoting DCs [15] loaded with autologous glioma lysate (UPCI 99-111) [16].
IL-4 Positive_regulation (promotes) of Gene_expression (production) of IL-12 in fibroblasts associated with glioma
1) Confidence 0.06 Published 2007 Journal J Transl Med Section Body Doc Link PMC2254376 Disease Relevance 0.89 Pain Relevance 0.03

General Comments

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