INT225667

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Context Info
Confidence 0.52
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.73
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

chromosome organization (Apc) plasma membrane (Apc) nucleus (Apc)
protein complex assembly (Apc) cytoplasm (Apc)
Anatomy Link Frequency
blood 1
Apc (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 11 99.40 Very High Very High Very High
Pain 10 70.00 Quite High
Piles 2 65.72 Quite High
ischemia 1 58.96 Quite High
Serotonin 4 36.84 Quite Low
imagery 13 24.64 Low Low
Central nervous system 14 5.00 Very Low Very Low Very Low
Cannabinoid 14 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Morphine 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 350 100.00 Very High Very High Very High
Epidermal Cyst 3 99.84 Very High Very High Very High
Osteoma 15 99.44 Very High Very High Very High
Colon Cancer 46 99.16 Very High Very High Very High
Cancer 102 96.20 Very High Very High Very High
Desmoid Disease 50 95.28 Very High Very High Very High
Increased Venous Pressure Under Development 8 93.04 High High
Cicatrix 3 81.36 Quite High
Pain 10 70.00 Quite High
Anorectal Disorders 2 65.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subsequent studies demonstrated that APC and ?
Transcription (demonstrated) of APC associated with familial adenomatous polyposis
1) Confidence 0.52 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 0.91 Pain Relevance 0
After a 15 min baseline recording of blood flow capsaicin (320 ?
Transcription (recording) of min in blood associated with qutenza
2) Confidence 0.44 Published 2008 Journal J Transl Med Section Body Doc Link PMC2254379 Disease Relevance 0.33 Pain Relevance 0.22
Jarvinen found that the median interval between the operation and the diagnosis of desmoid was a little over 2 years.85 The lifetime risk associated with these tumors in a Finnish and Italian registry was estimated to be approximately 21%.86,87 The most important risk factors are a positive family history, presence of osteomas or epidermoid cysts and an APC gene mutation between codons 1,444 and 1,578.86

Clinical Findings

Transcription (mutation) of APC associated with epidermal cyst, osteoma, cancer, familial adenomatous polyposis and desmoid disease
3) Confidence 0.10 Published 2008 Journal Ann Surg Oncol Section Body Doc Link PMC2518080 Disease Relevance 2.49 Pain Relevance 0.10

General Comments

This test has worked.

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