INT225706

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Context Info
Confidence 0.19
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.39
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Entpd8)
Anatomy Link Frequency
capsules 1
Entpd8 (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 62 99.54 Very High Very High Very High
Glutamate 20 93.08 High High
Bile 20 90.56 High High
antagonist 70 78.00 Quite High
long-term potentiation 2 48.16 Quite Low
depression 7 42.56 Quite Low
Central nervous system 15 37.92 Quite Low
Cholecystokinin 2 35.72 Quite Low
Neurotransmitter 7 5.04 Very Low Very Low Very Low
Inflammation 29 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 91.60 High High
Salivary Gland Disease 6 70.04 Quite High
Epilepsy 31 65.04 Quite High
Convulsion 11 51.60 Quite High
Hepatitis 2 43.48 Quite Low
Cirrhosis 10 42.88 Quite Low
Depression 7 42.56 Quite Low
Liver Disease 2 33.80 Quite Low
Cholangiocarcinoma 2 12.20 Low Low
Brain Injury 1 9.52 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of NTPDase8, ecto-5?
Gene_expression (presence) of NTPDase8
1) Confidence 0.19 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254478 Disease Relevance 0 Pain Relevance 0.33
NTPDase2 is detected on the BowmanÂ’s capsules of mouse and rat [199] and NTPDase8 on the luminal side of porcine renal tubules [174].
Gene_expression (detected) of NTPDase8 in capsules
2) Confidence 0.17 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254478 Disease Relevance 0.18 Pain Relevance 0.11
The mechanism for this is that ATP is rapidly broken down into adenosine by ectonucleotidases (E-NTPDase, E-NPP, alkaline phosphatises, and ecto-5?
Gene_expression (ecto) of E-NTPDase associated with adenocard
3) Confidence 0.07 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583203 Disease Relevance 0.21 Pain Relevance 0.16

General Comments

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