INT225782

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Context Info
Confidence 0.12
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (Enpp1) extracellular space (Enpp1) signal transduction (Tnfrsf11b)
extracellular region (Tnfrsf11b) proteinaceous extracellular matrix (Tnfrsf11b) plasma membrane (Enpp1)
Anatomy Link Frequency
artery 1
Tnfrsf11b (Mus musculus)
Enpp1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 39.24 Quite Low
Osteoarthritis 15 8.72 Low Low
depression 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Calcification 46 100.00 Very High Very High Very High
Metaplasia 1 53.20 Quite High
Aging 13 50.64 Quite High
Diabetes Mellitus 2 50.08 Quite High
Increased Venous Pressure Under Development 1 48.24 Quite Low
Renal Insufficiency 1 39.52 Quite Low
Osteoporosis 4 29.76 Quite Low
Osteoarthritis 15 8.72 Low Low
Disease 8 5.00 Very Low Very Low Very Low
Chondrocalcinosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, there was no gross alteration in expression of the physiologic artery calcification inhibitors matrix gla protein and osteoprotegerin in NPP1-/- mouse arterial cells [35].
osteoprotegerin Neg (no) Regulation (alteration) of NPP1 in artery associated with calcification
1) Confidence 0.12 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254483 Disease Relevance 0.74 Pain Relevance 0

General Comments

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