INT225784

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (Enpp1) extracellular space (Enpp1) plasma membrane (Enpp1)
Anatomy Link Frequency
chondrocytes 2
Il1 (Mus musculus)
Enpp1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 3 99.98 Very High Very High Very High
Inflammation 2 99.80 Very High Very High Very High
depression 2 93.28 High High
spinal inflammation 1 86.24 High High
Osteoarthritis 15 5.32 Low Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 99.80 Very High Very High Very High
Depression 2 93.28 High High
Calcification 46 90.44 High High
Disease 8 86.88 High High
Low Back Pain 1 86.24 High High
Congenital Anomalies 3 69.36 Quite High
Hyperostosis 1 56.16 Quite High
Syndrome 1 34.28 Quite Low
Aging 13 25.20 Quite Low
Osteoarthritis 15 5.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the inflammatory cytokine IL-1 depresses NPP1 expression, NPP activity, and extracellular PPi in chondrocytes [43].
IL-1 Negative_regulation (depresses) of Gene_expression (expression) of NPP1 in chondrocytes associated with inflammation and cytokine
1) Confidence 0.08 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254483 Disease Relevance 0.99 Pain Relevance 0.28

General Comments

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