INT225988

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 9
Disease Relevance 8.79
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
eye 1
[[Del(7)Tyr<c-1DThWb>-p]] (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 80 91.20 High High
cytokine 82 90.72 High High
tolerance 25 69.84 Quite High
imagery 4 10.72 Low Low
anesthesia 5 5.00 Very Low Very Low Very Low
isoflurane 5 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 195 100.00 Very High Very High Very High
Cold Sores 212 99.32 Very High Very High Very High
Infection 156 99.08 Very High Very High Very High
Injury 40 98.36 Very High Very High Very High
Ocular Injury 145 95.84 Very High Very High Very High
Viral Infection 4 93.04 High High
Pressure And Volume Under Development 37 92.56 High High
Corneal Neovascularization 4 92.28 High High
INFLAMMATION 88 91.20 High High
Corneal Opacity 16 91.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with pBTLA suppresses the systemic DTH responses of mice
Regulation (responses) of DTH associated with hypersensitivity
1) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 0.83 Pain Relevance 0.03
A significantly decreased DTH response was observed in the AC-injection group as well as in mice that received a penetrating injury at 72 h and 120 h following AC-injection of OVA.
Regulation (response) of DTH associated with injury and hypersensitivity
2) Confidence 0.02 Published 2008 Journal Molecular Vision Section Abstract Doc Link PMC2255028 Disease Relevance 0.67 Pain Relevance 0
A significant DTH response was also observed in the 24 h and 48 h “injury” group but not in the 72-h and 120-h group.
Regulation (response) of DTH associated with injury and hypersensitivity
3) Confidence 0.02 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2255028 Disease Relevance 1.12 Pain Relevance 0.13
Similarly, a strong DTH response was also noted in the PBS control group (Figure 2).


Regulation (response) of DTH associated with hypersensitivity
4) Confidence 0.02 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2255028 Disease Relevance 0.60 Pain Relevance 0.08
These results indicate that the breakdown of the eye’s integrity at an early stage following an AC injection could induce a DTH response and was able to prevent the induction of ACAID.
Regulation (response) of DTH in eye associated with hypersensitivity
5) Confidence 0.02 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2255028 Disease Relevance 0.92 Pain Relevance 0.12
The results showed that an AC injection of OVA could induce a decreased DTH response in association with an increased production of TGF-?
Regulation (response) of DTH associated with hypersensitivity
6) Confidence 0.02 Published 2008 Journal Molecular Vision Section Body Doc Link PMC2255028 Disease Relevance 0.73 Pain Relevance 0.03
This was also supported by our results for DTH responses in the mice.
Regulation (responses) of DTH associated with hypersensitivity
7) Confidence 0.02 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.48 Pain Relevance 0.13
DTH responses were measured in uninfected (naïve) and infected mice, including treated and control groups, on day 13 after HSV-1 infection.
Regulation (responses) of DTH associated with cold sores, hypersensitivity and infection
8) Confidence 0.02 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2965573 Disease Relevance 1.53 Pain Relevance 0
The pBTLA treated mice showed an impaired DTH response two weeks after HSV-1 infection compared to control mice.
Regulation (response) of DTH associated with cold sores, hypersensitivity and infection
9) Confidence 0.02 Published 2010 Journal Molecular Vision Section Abstract Doc Link PMC2965573 Disease Relevance 0.90 Pain Relevance 0.04

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