INT226109

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.89
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Prkag1) protein complex (Prkag1) response to stress (Prkag1)
Anatomy Link Frequency
vesicles 1
Prkag1 (Mus musculus)
Pain Link Frequency Relevance Heat
Cannabinoid 33 98.60 Very High Very High Very High
alcohol 12 89.64 High High
Endocannabinoid 35 86.80 High High
antagonist 16 83.52 Quite High
Glutamate 2 48.96 Quite Low
ischemia 5 45.92 Quite Low
agonist 48 40.04 Quite Low
tolerance 8 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 30 97.88 Very High Very High Very High
Increased Venous Pressure Under Development 10 95.12 Very High Very High Very High
Liver Disease 2 94.28 High High
Diabetes Mellitus 18 93.44 High High
Syndrome 2 92.12 High High
Hyperinsulinism 7 90.48 High High
Apoptosis 4 79.60 Quite High
Cancer 6 76.20 Quite High
Stress 18 74.12 Quite High
Metabolic Disorder 16 68.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Physiologically, exercise enables GLUT4 to translocate into plasma membrane from vesicles through AMPK.
Localization (translocate) of AMPK in vesicles
1) Confidence 0.43 Published 2010 Journal PPAR Research Section Body Doc Link PMC2929615 Disease Relevance 0.33 Pain Relevance 0
Rosiglitazone promotes AMPK-mediated insulin secretion via the phosphorylation of Kir6.2 subunit of the potassium (ATP) channel in ?
Localization (secretion) of AMPK
2) Confidence 0.41 Published 2010 Journal PPAR Research Section Body Doc Link PMC2929615 Disease Relevance 1.14 Pain Relevance 0
Ethanol has been shown to elicit a number of pathophysiological responses including compromised glucose transport and gastric acid secretion via an AMPK-dependent manner [29], [30], similar to our current finding.
Localization (secretion) of AMPK-dependent
3) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890411 Disease Relevance 0.36 Pain Relevance 0.04
Therefore, the effect of ghrelin on both AMPK and appetite is clearly dependent on an intact cannabinoid pathway.
Localization (appetite) of AMPK associated with cannabinoid
4) Confidence 0.13 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2258435 Disease Relevance 0.07 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox