INT226169

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.17
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Tpm1) cytoskeleton (Tpm1) embryo development (Tpm1)
protein complex (Tpm1) cytoplasm (Tpm1)
Anatomy Link Frequency
myofibril 2
Tpm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 92.92 High High
imagery 21 5.00 Very Low Very Low Very Low
Action potential 11 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 92.92 High High
Insulin Resistance 9 92.36 High High
Acidosis 6 91.56 High High
Cancer 5 86.36 High High
Diabetes Mellitus 5 86.04 High High
Sepsis 5 85.64 High High
Disease 8 85.12 High High
Chronic Renal Failure 28 83.92 Quite High
Frailty 19 82.68 Quite High
Nervous System Malformation 1 74.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The initial step in this process is activation of caspase-3 to cleave the myofibril into its components (actin, myosin, troponin, and tropomyosin).
Positive_regulation (activation) of Gene_expression (actin) of tropomyosin in myofibril
1) Confidence 0.49 Published 2007 Journal Pediatr Nephrol Section Abstract Doc Link PMC2259254 Disease Relevance 1.10 Pain Relevance 0.05
At the same time, we observe substantial increases in expression of 1,012 genes, including cardiac structural genes such as tropomyosin 1 and 2 (TPM1, 2, ?
Positive_regulation (increases) of Gene_expression (expression) of TPM1
2) Confidence 0.14 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565131 Disease Relevance 0.07 Pain Relevance 0

General Comments

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