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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Trim63)
Anatomy Link Frequency
nucleus 2
Trim63 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 85.36 High High
cytokine 3 78.48 Quite High
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 85.36 High High
Cancer 5 82.72 Quite High
Necrosis 1 82.24 Quite High
Frailty 19 80.64 Quite High
Hypertrophy 2 80.16 Quite High
Insulin Resistance 9 62.84 Quite High
Chronic Renal Failure 28 50.00 Quite Low
Diabetes Mellitus 5 30.04 Quite Low
Acidosis 6 29.16 Quite Low
Sepsis 5 28.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Akt-P also phosphorylates the forkhead (FoxO) transcription factor, preventing it from entering the nucleus to promote expression of atrogin-1, MuRF-1, and other atrogenes, thereby blocking protein degradation.
Negative_regulation (blocking) of Gene_expression (expression) of MuRF-1 in nucleus
1) Confidence 0.12 Published 2007 Journal Pediatr Nephrol Section Body Doc Link PMC2259254 Disease Relevance 0.68 Pain Relevance 0.12

General Comments

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