INT226190

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pik3cb) signal transduction (Pik3cb) extracellular space (Igf1)
extracellular region (Igf1) cell adhesion (Pik3cb) nucleus (Pik3cb)
Anatomy Link Frequency
muscle 2
Igf1 (Rattus norvegicus)
Pik3cb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 10 46.80 Quite Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 9 98.52 Very High Very High Very High
Diabetes Mellitus 5 96.88 Very High Very High Very High
Chronic Renal Failure 28 96.32 Very High Very High Very High
Acidosis 6 96.00 Very High Very High Very High
Sepsis 5 95.60 Very High Very High Very High
Frailty 19 77.84 Quite High
Disease 8 77.04 Quite High
Acid Base Imbalance 6 68.28 Quite High
INFLAMMATION 13 46.80 Quite Low
Syndrome 1 37.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In normal muscle, binding of insulin or insulin-like growth factor (IGF)-1 to their receptors increases the activities of PI3K and its downstream target, Akt.
IGF Binding (binding) of in muscle Positive_regulation (increases) of PI3K
1) Confidence 0.17 Published 2007 Journal Pediatr Nephrol Section Body Doc Link PMC2259254 Disease Relevance 1.04 Pain Relevance 0

General Comments

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