INT226207

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Ins1, Pik3cb) carbohydrate metabolic process (Ins1) cytosol (Pik3cb)
extracellular space (Ins1) signal transduction (Pik3cb) extracellular region (Ins1)
Anatomy Link Frequency
muscle 4
Ins1 (Mus musculus)
Pik3cb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 20 46.80 Quite Low
cytokine 6 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Inflammatory marker 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Insulin Resistance 18 98.52 Very High Very High Very High
Diabetes Mellitus 10 96.88 Very High Very High Very High
Chronic Renal Failure 56 96.32 Very High Very High Very High
Acidosis 12 96.00 Very High Very High Very High
Sepsis 10 95.60 Very High Very High Very High
Frailty 38 77.84 Quite High
Disease 16 77.04 Quite High
Acid Base Imbalance 12 68.28 Quite High
INFLAMMATION 26 46.80 Quite Low
Syndrome 2 37.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In normal muscle, binding of insulin or insulin-like growth factor (IGF)-1 to their receptors increases the activities of PI3K and its downstream target, Akt.
insulin Binding (binding) of in muscle Positive_regulation (increases) of PI3K
1) Confidence 0.01 Published 2007 Journal Pediatr Nephrol Section Body Doc Link PMC2259254 Disease Relevance 1.04 Pain Relevance 0
In normal muscle, binding of insulin or insulin-like growth factor (IGF)-1 to their receptors increases the activities of PI3K and its downstream target, Akt.
insulin Binding (binding) of in muscle Positive_regulation (increases) of PI3K
2) Confidence 0.01 Published 2007 Journal Pediatr Nephrol Section Body Doc Link PMC2259254 Disease Relevance 1.04 Pain Relevance 0

General Comments

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