INT226210

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Akt1, Mul1) signal transduction (Akt1, Mul1) nucleus (Akt1, Mul1)
mitochondrion (Mul1) transport (Akt1) aging (Akt1)
Anatomy Link Frequency
muscle 1
Akt1 (Mus musculus)
Mul1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 96.16 Very High Very High Very High
cytokine 3 51.92 Quite High
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 96.16 Very High Very High Very High
Muscular Atrophy 4 86.24 High High
Acidosis 6 83.92 Quite High
Chronic Renal Failure 28 78.40 Quite High
Frailty 19 76.40 Quite High
Insulin Resistance 9 65.60 Quite High
Necrosis 1 50.00 Quite Low
Cancer 5 49.64 Quite Low
Acid Base Imbalance 6 37.76 Quite Low
Diabetes Mellitus 5 35.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The influence of Akt on the other E3 ubiquitin ligase involved in muscle proteolysis, MuRF-1, is not as clearly established, and it may be linked to inflammation, as activation of NF-?
Akt Regulation (influence) of E3 ubiquitin ligase in muscle associated with inflammation
1) Confidence 0.04 Published 2007 Journal Pediatr Nephrol Section Body Doc Link PMC2259254 Disease Relevance 0.60 Pain Relevance 0.10

General Comments

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