INT226298

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (TGM1) transferase activity, transferring acyl groups (TGM1)
Anatomy Link Frequency
eye 2
TGM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 7 46.12 Quite Low
Inflammatory response 3 40.84 Quite Low
cytokine 3 35.28 Quite Low
Inflammation 3 34.88 Quite Low
Sicca syndrome 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 78 99.48 Very High Very High Very High
Corneal Disease 10 98.12 Very High Very High Very High
Stress 1 92.04 High High
Cancer 4 84.00 Quite High
Infection 33 83.72 Quite High
Adhesions 6 82.08 Quite High
Hyperopia 2 77.60 Quite High
Viral Infection 6 75.44 Quite High
Williams-beuren Syndrome 1 73.56 Quite High
Congenital Anomalies 1 73.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We wonder if this increased expression of transglutaminase 1 may contribute to the increased prevalence of dry eye in women [55].
Positive_regulation (increased) of Gene_expression (expression) of transglutaminase 1 in eye associated with corneal disease
1) Confidence 0.24 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2790476 Disease Relevance 0.99 Pain Relevance 0
In experiments using non-polarized cervicovaginal tissue explants, the toxic nature of LiJ was more apparent, with a 30 minute exposure to 10% LiJ causing significant toxicity, suggesting that toxicity would be higher where the cervicovaginal mucosa was damaged.
Positive_regulation (causing) of Gene_expression (apparent) of LiJ associated with toxicity
2) Confidence 0.23 Published 2008 Journal Retrovirology Section Body Doc Link PMC2259360 Disease Relevance 0.63 Pain Relevance 0
LiJ was then removed by washing (4 × 200 ?
Positive_regulation (removed) of Gene_expression (removed) of LiJ
3) Confidence 0.23 Published 2008 Journal Retrovirology Section Body Doc Link PMC2259360 Disease Relevance 0.40 Pain Relevance 0
In experiments using non-polarized cervicovaginal tissue explants, the toxic nature of LiJ was more apparent, with a 30 minute exposure to 10% LiJ causing significant toxicity, suggesting that toxicity would be higher where the cervicovaginal mucosa was damaged.
Positive_regulation (causing) of Gene_expression (apparent) of LiJ associated with toxicity
4) Confidence 0.23 Published 2008 Journal Retrovirology Section Body Doc Link PMC2259360 Disease Relevance 0.63 Pain Relevance 0

General Comments

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