INT226378

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (INCENP, SOCS1) cytosol (INCENP, SOCS1) nucleus (INCENP, SOCS1)
chromosome segregation (INCENP) protein complex (INCENP) chromosome (INCENP)
Anatomy Link Frequency
epithelial cells 2
INCENP (Homo sapiens)
SOCS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 91 88.80 High High
Inflammation 96 33.44 Quite Low
antagonist 34 5.00 Very Low Very Low Very Low
chemokine 23 5.00 Very Low Very Low Very Low
agonist 20 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 315 99.68 Very High Very High Very High
Targeted Disruption 20 80.08 Quite High
Disease 17 49.36 Quite Low
Hypersensitivity 9 45.28 Quite Low
Sprains And Strains 1 44.20 Quite Low
Conjunctiva Disease 1 38.72 Quite Low
Rhinitis 11 34.48 Quite Low
INFLAMMATION 103 33.44 Quite Low
Eosinophilia 19 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro this SNPs enhances the transcription of SOCS1 in human lung epithelial cells, but reduces phosphorylation of STAT1 stimulated with IFN-?
In vitro Positive_regulation (enhances) of Transcription (transcription) of SOCS1 in epithelial cells
1) Confidence 0.01 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.41 Pain Relevance 0.13

General Comments

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