INT226427

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 4.07
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (FABP4) lipid particle (FABP4) nucleus (FABP4)
lipid metabolic process (FABP4) cytoplasm (FABP4)
Anatomy Link Frequency
epithelial cells 2
adipocyte 2
plasma 1
FABP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 138 99.26 Very High Very High Very High
cINOD 34 72.04 Quite High
antagonist 76 68.24 Quite High
chemokine 46 45.28 Quite Low
withdrawal 8 36.56 Quite Low
Analgesic 3 35.76 Quite Low
Inflammation 218 5.00 Very Low Very Low Very Low
cytokine 184 5.00 Very Low Very Low Very Low
Chronic pancreatitis 26 5.00 Very Low Very Low Very Low
alcohol 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatty Liver 6 100.00 Very High Very High Very High
Obesity 8 99.76 Very High Very High Very High
Cancer 242 96.56 Very High Very High Very High
Liposarcoma 40 92.60 High High
Eosinophilia 38 92.40 High High
Hyperplasia 18 89.80 High High
Asthma 630 84.56 Quite High
Disease Progression 10 79.84 Quite High
INFLAMMATION 238 71.56 Quite High
Sprains And Strains 7 67.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Linear mixed model regression was used to analyze changes over time in plasma FABP levels.
Spec (analyze) Gene_expression (levels) of FABP in plasma
1) Confidence 0.44 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2599890 Disease Relevance 0.06 Pain Relevance 0
The expression of markers of adipocyte differentiation such as adipsin, aP2, and PPAR?
Gene_expression (expression) of aP2 in adipocyte
2) Confidence 0.33 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 1.29 Pain Relevance 0
The probability level of them are realized between 81% and 89%, because AP1, AP2, and AP3 are found in, respectively 15, 12, 15 from 28 inactive molecules in total.
Gene_expression (found) of AP2
3) Confidence 0.29 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2943087 Disease Relevance 0 Pain Relevance 0
By

quantitative RT-PCR, levels of adipsin, fatty acid-binding protein (FABP), and

Gene_expression (levels) of FABP
4) Confidence 0.25 Published 2008 Journal PPAR Research Section Body Doc Link PMC2605846 Disease Relevance 0.86 Pain Relevance 0
The adipocyte/macrophage fatty acid–binding protein (FABP) aP2 is expressed in bronchial epithelial cells and it is strongly upregulated by both IL-4 and IL-13 in a STAT6-dependent manner.
Gene_expression (expressed) of aP2 in epithelial cells
5) Confidence 0.16 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.60 Pain Relevance 0
The adipocyte/macrophage fatty acid–binding protein (FABP) aP2 is expressed in bronchial epithelial cells and it is strongly upregulated by both IL-4 and IL-13 in a STAT6-dependent manner.
Gene_expression (expressed) of FABP in epithelial cells
6) Confidence 0.16 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.60 Pain Relevance 0
agonist, we investigated its effects on the levels of L-FABP and aP2, two established PPAR?
Gene_expression (levels) of aP2 associated with agonist
7) Confidence 0.11 Published 2008 Journal Journal of Medicinal Chemistry Section Body Doc Link PMC2651753 Disease Relevance 0 Pain Relevance 0.12
to a PPRE-containing oligonucleotide and induced expression of liver fatty-acid binding protein (L-FABP) and adipocyte fatty acid-binding protein (aP2), two established PPAR?
Gene_expression (expression) of aP2 in adipocyte associated with fatty liver
8) Confidence 0.09 Published 2008 Journal Journal of Medicinal Chemistry Section Abstract Doc Link PMC2651753 Disease Relevance 0.17 Pain Relevance 0.23
On the other hand, many researchers have found that transcription factors (e.g., c-Myb, c-Myc/Myn, E2F, CREB, Ap1, Ap2, Sp1, and NF-?
Gene_expression (e.g.) of Ap2
9) Confidence 0.09 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2862018 Disease Relevance 0.24 Pain Relevance 0
On the other hand, many researchers have found that transcription factors (e.g., c-Myb, c-Myc/Myn, E2F, CREB, Ap1, Ap2, Sp1, and NF-?
Gene_expression (/) of Ap2
10) Confidence 0.09 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2862018 Disease Relevance 0.24 Pain Relevance 0

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