INT226464

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Context Info
Confidence 0.73
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.69
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL19) extracellular space (IL19) extracellular region (IL19)
Anatomy Link Frequency
PC-3 1
IL19 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 31 100.00 Very High Very High Very High
cytokine 103 96.60 Very High Very High Very High
antagonist 35 93.00 High High
Inflammation 109 74.88 Quite High
chemokine 23 44.92 Quite Low
agonist 21 5.00 Very Low Very Low Very Low
Inflammatory response 10 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 161 98.76 Very High Very High Very High
Depression 48 96.72 Very High Very High Very High
Asthma 315 93.52 High High
Metastasis 33 93.00 High High
INFLAMMATION 121 74.88 Quite High
Eosinophilia 19 67.80 Quite High
Occupational Lung Diseases 15 31.44 Quite Low
Wound Healing 3 30.92 Quite Low
Colon Cancer 8 7.40 Low Low
Hypersensitivity 9 6.96 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gelatin zymography assays indicated that THL dose-dependently inhibited the secretion of MMP-2 and MMP-9 in MDA-MB-231, H1299, PC-3 and CT-26 cancer cells (Fig 2A).
Localization (secretion) of MDA in PC-3 associated with cancer and metalloproteinase
1) Confidence 0.73 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2880989 Disease Relevance 0.86 Pain Relevance 0.44
Seven SNPs of the genomic region of IL10, IL19, IL20, and IL24 genes (IL10 cluster) were analyzed in 153 Estonian patients with MDD and 277 healthy control subjects.
Localization (region) of IL19 associated with depression
2) Confidence 0.69 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2648955 Disease Relevance 0.24 Pain Relevance 0
 ; molecules related to IL-10 (IL-19, IL-20, IL-22, IL-24, IL-26); and the IFN-?
Localization (related) of IL-19
3) Confidence 0.05 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.59 Pain Relevance 0.28

General Comments

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