INT226488

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.90
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL4R) extracellular space (IL4R) extracellular region (IL4R)
plasma membrane (IL4R)
IL4R (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 192 94.64 High High
chemokine 46 85.12 High High
cytokine 182 84.52 Quite High
withdrawal 4 84.52 Quite High
antagonist 68 76.68 Quite High
agonist 40 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
methotrexate 8 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 630 99.50 Very High Very High Very High
Pneumonia 14 95.44 Very High Very High Very High
Metaplasia 12 91.20 High High
Eosinophilia 38 87.44 High High
Occupational Lung Diseases 30 85.72 High High
Hyperplasia 18 73.12 Quite High
INFLAMMATION 206 71.52 Quite High
Rhinitis 22 49.76 Quite Low
Pulmonary Eosinophilia 2 38.56 Quite Low
Disease 34 35.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data support the potential utility of a dual IL-4 and IL-13 oligonucleotide inhibitor in asthma, and suggest that local inhibition of IL-4R?
Negative_regulation (inhibition) of IL-4R associated with asthma
1) Confidence 0.01 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 1.01 Pain Relevance 0.22
ASO) specifically inhibits IL-4R?
Negative_regulation (inhibits) of IL-4R
2) Confidence 0.01 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.89 Pain Relevance 0.22

General Comments

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