INT226490

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.99
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
CLC 1
ST2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 183 90.48 High High
aspirin 7 75.68 Quite High
Inflammation 218 63.84 Quite High
tolerance 2 32.96 Quite Low
antagonist 68 5.00 Very Low Very Low Very Low
chemokine 52 5.00 Very Low Very Low Very Low
agonist 40 5.00 Very Low Very Low Very Low
Inflammatory response 14 5.00 Very Low Very Low Very Low
methotrexate 8 5.00 Very Low Very Low Very Low
fibrosis 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chronic Sinusitis 14 96.48 Very High Very High Very High
Asthma 647 96.20 Very High Very High Very High
Eosinophilic Esophagitis 5 84.04 Quite High
Injury 34 83.44 Quite High
Targeted Disruption 40 80.40 Quite High
Multiple Organ Failure 2 76.96 Quite High
Infection 75 73.52 Quite High
INFLAMMATION 234 63.84 Quite High
Rhinitis 84 58.16 Quite High
Hemorrhagic Shock 5 57.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our qRT-PCR results for CCL13, CCL18, CRISP3, EMR3, and IL1RL1 (ST2) (Figure 2) and the increased presence of CLC (Figure 3) and CCL18 [17] protein in separately collected airway specimens from CRS or asthmatic patients, in accordance with their increased mRNA levels in our aCRSwNP patients, further support the validity of our exon array data.
Localization (presence) of ST2 in CLC associated with asthma and chronic sinusitis
1) Confidence 0.31 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2897889 Disease Relevance 0.59 Pain Relevance 0.13
Three distinct types of ST2 (also known as T1, Fit-1, and DER4) gene products have been cloned; a soluble secreted form (ST2), a transmembrane receptor form (ST2L), and a variant form (ST2V).
Localization (secreted) of ST2
2) Confidence 0.22 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.50 Pain Relevance 0.16
Three distinct types of ST2 (also known as T1, Fit-1, and DER4) gene products have been cloned; a soluble secreted form (ST2), a transmembrane receptor form (ST2L), and a variant form (ST2V).
Localization (secreted) of ST2
3) Confidence 0.22 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.43 Pain Relevance 0.15
A recent large observational and descriptive study found a mean thenar StO2 of 87 ± 6% in 707 normal human volunteers [9].
Localization (found) of StO2
4) Confidence 0.10 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2714076 Disease Relevance 0.34 Pain Relevance 0
These were separated into the ST2-mod group (n?
Localization (separated) of ST2
5) Confidence 0.07 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2821909 Disease Relevance 0.14 Pain Relevance 0

General Comments

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