INT226509

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.40
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Il1rl1, Mapk8) mitochondrion (Mapk8) intracellular (Il1rl1)
cytoplasm (Mapk8) cytosol (Mapk8) extracellular space (Il1rl1)
Il1rl1 (Mus musculus)
Mapk8 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 2 99.12 Very High Very High Very High
cytokine 182 71.68 Quite High
Inflammation 192 25.08 Quite Low
antagonist 68 5.00 Very Low Very Low Very Low
chemokine 46 5.00 Very Low Very Low Very Low
agonist 40 5.00 Very Low Very Low Very Low
Inflammatory response 12 5.00 Very Low Very Low Very Low
methotrexate 8 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilia 38 91.16 High High
Asthma 630 51.16 Quite High
Targeted Disruption 40 41.64 Quite Low
INFLAMMATION 206 25.08 Quite Low
Eczema 8 13.60 Low Low
Disease 34 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 30 5.00 Very Low Very Low Very Low
Rhinitis 22 5.00 Very Low Very Low Very Low
Hypersensitivity 18 5.00 Very Low Very Low Very Low
Hyperplasia 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, ST2L is able to activate the transcription factor AP-1; increase phosphorylation of c-Jun, and activate the MAP kinases c-Jun N-terminal kinase (JNK), p42/p44 and p38.
ST2L Positive_regulation (activate) of Gene_expression (kinase) of JNK
1) Confidence 0.05 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.20 Pain Relevance 0.15
Additionally, ST2L is able to activate the transcription factor AP-1; increase phosphorylation of c-Jun, and activate the MAP kinases c-Jun N-terminal kinase (JNK), p42/p44 and p38.
ST2L Positive_regulation (activate) of Gene_expression (kinase) of c-Jun N-terminal
2) Confidence 0.05 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.20 Pain Relevance 0.15

General Comments

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