INT226531

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL4) extracellular region (IL4) RNA binding (Gtf3a)
nucleus (Gtf3a) intracellular (Gtf3a) DNA binding (Gtf3a)
Anatomy Link Frequency
T lymphocytes 2
Gtf3a (Mus musculus)
IL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 23 31.56 Quite Low
cytokine 91 10.80 Low Low
Inflammation 96 5.00 Very Low Very Low Very Low
antagonist 34 5.00 Very Low Very Low Very Low
agonist 20 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 315 95.28 Very High Very High Very High
Eosinophilia 19 78.68 Quite High
Hyperplasia 9 76.08 Quite High
Targeted Disruption 20 66.16 Quite High
Metaplasia 6 39.40 Quite Low
INFLAMMATION 103 5.00 Very Low Very Low Very Low
Disease 17 5.00 Very Low Very Low Very Low
Occupational Lung Diseases 15 5.00 Very Low Very Low Very Low
Rhinitis 11 5.00 Very Low Very Low Very Low
Hypersensitivity 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of c-MAF appear to be fairly selective, since in vitro studies have demonstrated that this factor is critical for the production of IL-4, but not for IL-5 or IL-13 [129,130]. c-Maf expression in T lymphocytes is regulated by IL-4 levels during Th differentiation.
factor Neg (not) Positive_regulation (critical) of Gene_expression (production) of IL-4 in T lymphocytes
1) Confidence 0.00 Published 2008 Journal J Occup Med Toxicol Section Body Doc Link PMC2259400 Disease Relevance 0.51 Pain Relevance 0

General Comments

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