INT226597

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (DRGX)
Anatomy Link Frequency
neurons 2
DRGX (Homo sapiens)
Pain Link Frequency Relevance Heat
hyperexcitability 3 100.00 Very High Very High Very High
Pain 15 98.96 Very High Very High Very High
addiction 7 75.04 Quite High
Neuronal excitability 1 8.00 Low Low
Lasting pain 2 5.00 Very Low Very Low Very Low
sodium channel 2 5.00 Very Low Very Low Very Low
burning pain 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Congenital analgesia 1 5.00 Very Low Very Low Very Low
Paroxysmal extreme pain disorder 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Erythermalgia 25 98.16 Very High Very High Very High
Pain 15 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Somatoform Disorder 2 5.00 Very Low Very Low Very Low
Congenital Pain Insensitivity 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low
Non-diabetic Peripheral Neuropathy 1 5.00 Very Low Very Low Very Low
Ganglion Cysts 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Febrile Convulsions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These changes of the biophysical properties of NaV1.7 are expected to contribute to hyperexcitability of DRG neurons, which underlies painful symptoms of erythromelalgia.
Regulation (contribute) of Localization (hyperexcitability) of DRG in neurons associated with pain, erythermalgia and hyperexcitability
1) Confidence 0.08 Published 2008 Journal Mol Pain Section Body Doc Link PMC2262064 Disease Relevance 0.32 Pain Relevance 0.21

General Comments

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