INT226627

Context Info Confidence 0.06 First Reported 2008 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 0.82 Pain Relevance 0

nucleus (Tnip1) cytoplasm (Tnip1)

Tnip1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammatory response 1 34.68 chemokine 5 28.92 Inflammation 62 5.00 cytokine 8 5.00 metalloproteinase 8 5.00 Bioavailability 6 5.00 Inflammatory mediators 6 5.00 Kinase C 4 5.00 Potency 4 5.00 ischemia 2 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 75 88.16 Asthma 8 79.72 Pulmonary Disease 4 79.28 Toxicity 8 57.60 Atherosclerosis 106 50.00 INFLAMMATION 59 34.32 Disease 12 9.84 Stress 38 5.00 Disorder Of Lipid Metabolism 18 5.00 Infection 10 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The sorting of CD4 from early endosomes into late endosomes/MVBs during Nef-induced downregulation has been shown to be dependent on the interaction of Nef with the ?

Positive_regulation (dependent) of Nef Binding (interaction) of

1) Confidence 0.06 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.23 Pain Relevance 0

The greater retention of UFP could be partly due to increased Van der Waals forces or electrostatic interactions, all of which contributes to "adhesive interactions" [108,109].

Positive_regulation (increased) of Van Binding (interactions) of

2) Confidence 0.02 Published 2009 Journal Part Fibre Toxicol Section Body Doc Link PMC2761850 Disease Relevance 0.29 Pain Relevance 0

The greater retention of UFP could be partly due to increased Van der Waals forces or electrostatic interactions, all of which contributes to "adhesive interactions" [108,109].

Positive_regulation (due) of Van Binding (interactions) of

3) Confidence 0.02 Published 2009 Journal Part Fibre Toxicol Section Body Doc Link PMC2761850 Disease Relevance 0.30 Pain Relevance 0

General Comments

This test has worked.