INT226722

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cxcr4) endoplasmic reticulum (Sdf2l1) signal transducer activity (Cxcr4)
signal transduction (Cxcr4) plasma membrane (Cxcr4) cytoplasmic membrane-bounded vesicle (Cxcr4)
Cxcr4 (Mus musculus)
Sdf2l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 75 98.64 Very High Very High Very High
Infection 10 5.00 Very Low Very Low Very Low
Superinfection 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that HA-CXCR4, like EGFR, is dependent on TSG101 function for SDF-1 mediated degradation.


CXCR4 Positive_regulation (dependent) of Protein_catabolism (degradation) of SDF-1
1) Confidence 0.02 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.30 Pain Relevance 0

General Comments

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