INT226751

Context Info Confidence 0.07 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.14 Pain Relevance 0

endosome (Tsg101, Vps28) transport (Tsg101, Vps28) cytoplasm (Tsg101, Vps28) plasma membrane (Tsg101, Vps28) cell differentiation (Tsg101) cytosol (Vps28)

Tsg101 (Mus musculus) Vps28 (Mus musculus)

Pain Link Frequency Relevance Heat Kinase C 4 5.00 imagery 2 5.00 chemokine 1 5.00 Inflammatory response 1 5.00 Opioid 1 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 75 77.76 Infection 10 5.00 Superinfection 4 5.00 Apoptosis 4 5.00 Cancer 3 5.00 INFLAMMATION 1 5.00 Cytomegalovirus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Overexpression of full length TSG101 has been shown to inhibit ESCRT-I function and block EGF-induced EGFR downregulation [14,32].

TSG101 Negative_regulation (inhibit) of ESCRT-I

1) Confidence 0.07 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.14 Pain Relevance 0

General Comments

This test has worked.