INT226755

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cxcr4, Cd4) endosome (Cxcr4) signal transduction (Cxcr4)
cell adhesion (Cd4) cytoplasmic membrane-bounded vesicle (Cxcr4) enzyme binding (Cd4)
Cxcr4 (Mus musculus)
Cd4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 1 16.28 Low Low
chemokine 1 10.52 Low Low
Kinase C 4 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 75 94.76 High High
INFLAMMATION 1 15.92 Low Low
Infection 10 5.00 Very Low Very Low Very Low
Superinfection 4 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SDF-1-induced downregulation of CXCR4 and PMA-induced downregulation of CD4 were monitored in cells depleted of endogenous TSG101 using siRNA directed against TSG101.
CXCR4 Negative_regulation (downregulation) of CD4
1) Confidence 0.15 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.38 Pain Relevance 0

General Comments

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