INT226758

Context Info Confidence 0.02 First Reported 2008 Last Reported 2008 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.30 Pain Relevance 0.10

plasma membrane (Gpbar1, Vps28) cytosol (Vps28) endosome (Vps28) transport (Vps28) signal transduction (Gpbar1) cytoplasm (Vps28)

Gpbar1 (Mus musculus) Vps28 (Mus musculus)

Pain Link Frequency Relevance Heat Opioid 1 99.62 Kinase C 4 5.00 imagery 2 5.00 chemokine 1 5.00 Inflammatory response 1 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 75 70.80 Infection 10 5.00 Superinfection 4 5.00 Apoptosis 4 5.00 Cancer 3 5.00 INFLAMMATION 1 5.00 Cytomegalovirus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For example, sorting and lysosomal degradation of the Delta Opioid Receptor (DOR), a GPCR, is Hrs and Vps4 dependent but does not require TSG101 (ESCRT-I) [21].

GPCR Neg (not) Positive_regulation (require) of ESCRT-I associated with opioid

1) Confidence 0.02 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.30 Pain Relevance 0.10

General Comments

This test has worked.