INT226785

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.65
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Angpt2, Lep) extracellular region (Angpt2, Lep) cell differentiation (Angpt2)
intracellular (Lep) lipid metabolic process (Lep) signal transduction (Angpt2)
Angpt2 (Rattus norvegicus)
Lep (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 21 100.00 Very High Very High Very High
Inflammatory mediators 4 100.00 Very High Very High Very High
cytokine 1 98.44 Very High Very High Very High
Somatostatin 9 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 100.00 Very High Very High Very High
Insulin Resistance 16 100.00 Very High Very High Very High
Hypertension 15 96.72 Very High Very High Very High
Pressure And Volume Under Development 52 87.92 High High
Sprains And Strains 1 82.80 Quite High
Metabolic Syndrome 16 82.68 Quite High
Disease 4 81.40 Quite High
Stress 3 67.64 Quite High
Hypoxia 1 66.12 Quite High
Obesity 3 61.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ang-II, in turn, initiates the gene expression of multiple pro-inflammatory mediators, interrupts the anti-inflammatory effects of Insulin [34], promotes IR [35] and stimulates the release of leptin, a prothrombotic and pro-inflammatory cytokine that activates an array of immune functions [36].
Ang-II Positive_regulation (stimulates) of Localization (release) of leptin associated with inflammatory mediators, inflammation, insulin resistance and cytokine
1) Confidence 0.01 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2262079 Disease Relevance 1.65 Pain Relevance 0.36

General Comments

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