INT226888

Context Info Confidence 0.13 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.11 Pain Relevance 0

plasma membrane (Gbp2) GTPase activity (Gbp2)

Gbp2 (Mus musculus)

Pain Link Frequency Relevance Heat Eae 1 7.04 Inflammation 22 5.00 cytokine 11 5.00 interstitial cystitis 3 5.00 Inflammatory response 2 5.00 Inflammatory stimuli 2 5.00 imagery 2 5.00 sodium channel 1 5.00 chemokine 1 5.00 Glutamate receptor 1 5.00

Disease Link Frequency Relevance Heat Cancer 26 59.24 Overactive Bladder 18 40.36 Disease 3 38.68 Reproductive System Disorders 1 6.28 INFLAMMATION 26 5.00 Bladder Cancer 9 5.00 Death 5 5.00 Mycobacterial Infection 4 5.00 Apoptosis 4 5.00 Interstitial Cystitis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

With the exception of SEMA5A, FVBP1, IGFBP3, and SELE, these results indicate that chronic treatment with BCG and to a lesser extent acute BCG induced up-regulation of the following genes as was predicted by the mRNA-level analysis: ARL6, CSK, DNAJC5, FAF1, GBP2, GZMA, HLA-DRB1, IL17b, INDO, MAP3K8, SMAD6, TFEB, VCAM1, and WISP2.

Positive_regulation (induced) of GBP2

1) Confidence 0.13 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2262873 Disease Relevance 0.11 Pain Relevance 0

General Comments

This test has worked.