INT226909

Context Info Confidence 0.07 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.18 Pain Relevance 0

transport (Slc11a1) mitochondrion (Nfkb1) DNA binding (Nfkb1) protein complex (Nfkb1) cytoplasm (Nfkb1) cytosol (Nfkb1)

Nfkb1 (Mus musculus) Slc11a1 (Mus musculus)

Pain Link Frequency Relevance Heat Eae 2 45.52 Inflammation 44 5.00 cytokine 22 5.00 interstitial cystitis 6 5.00 Inflammatory response 4 5.00 Inflammatory stimuli 4 5.00 imagery 4 5.00 sodium channel 2 5.00 chemokine 2 5.00 Glutamate receptor 2 5.00

Disease Link Frequency Relevance Heat Cancer 52 90.40 Injury 6 41.76 Overactive Bladder 36 18.04 Disease 6 16.36 INFLAMMATION 52 5.00 Bladder Cancer 18 5.00 Death 10 5.00 Mycobacterial Infection 8 5.00 Apoptosis 8 5.00 Interstitial Cystitis 6 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

To further confirm this finding, we tested whether the BCG-induced increased binding of NF-kappaB would lead to up-regulation of transcripts known to possess a p65 binding site.

Positive_regulation (increased) of NF-kappaB Binding (binding) of BCG

1) Confidence 0.07 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2262873 Disease Relevance 0.09 Pain Relevance 0

To further confirm this finding, we tested whether the BCG-induced increased binding of NF-kappaB would lead to up-regulation of transcripts known to possess a p65 binding site.

Positive_regulation (induced) of NF-kappaB Binding (binding) of BCG

2) Confidence 0.07 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2262873 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.